Time: Tuesday, June 2, 2026, 6:30–8:00 PM

Location: Classroom A on 1st floor, Frontier RTP, 800 Park Offices Dr, Durham, NC 27713

Title:
Building an Integrated AI-Driven Oligonucleotide Therapy Platform: From Webserver Architecture to Personalized Medicine

Introduction:
This talk presents the end-to-end architecture and development of an AI-driven web platform designed for oligonucleotide therapeutics (siRNA/ASO). Leveraging Claude Code, we developed a comprehensive system that integrates an intuitive front-end user interface with a robust back-end database tailored for high-throughput on- and off-target sequence analysis. Furthermore, we demonstrate the platform's real-world application in individualized gene therapy, showcasing how it processes human patient sequencing data to accelerate custom therapeutic design.

Speaker: Mr. Jeff Du

Bio:
Mr. Jeff Du is a bioinformatics scientist, with experience across bioinformatics, biostatistics, pharmaceutical science, and anti-cancer drug research. His work spans omics data mining, NGS and clinical data analysis, machine learning, cloud and high-performance computing, and bioinformatics pipeline development. He earned an M.S. from Duke University.

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